MioMama
Is Advil Safe in Pregnancy
Status
avoidReason
FDA advises avoiding NSAIDs at 20 weeks or later in pregnancy; after 30 weeks they may harm the fetus.
Drug Information
Safe Amount
Dosage must be determined by your provider based on individual risk/benefit.
Effects
- Pregnancy
- Risk of oligohydramnios after 20 weeks; avoid in the third trimester unless a clinician directs use.
- Mother
- May reduce pain and fever, but pregnancy use needs provider review due to fetal risks.
- Baby
- Can cause low amniotic fluid, fetal kidney problems, and after about 30 weeks may cause fetal heart/blood-flow problems.
Trimester Notes
- 1st Trimester
- Use only if your provider says it is needed. Official guidance is limited, so provider review is important.
- 2nd Trimester
- FDA advises avoiding NSAIDs at 20 weeks or later unless specifically recommended. If needed, use the lowest dose for the shortest time under medical guidance.
- 3rd Trimester
- Avoid in the last 3 months of pregnancy. FDA warns of fetal heart/blood-flow problems and delivery complications.
Conditions & Warnings
- Consult OB/GYN or prescriber
- OTC pregnancy dosing limits may apply
- Avoid NSAIDs at 20 weeks or later unless your provider specifically recommends it
Alternatives
- Acetaminophen may be considered if your OB/GYN says it is appropriate
- Non-medicine options for pain relief as advised by your clinician
References
- FDA: Avoid Use of NSAIDs in Pregnancy at 20 Weeks or Later
https://www.fda.gov/safety/medical-product-safety-information/nonsteroidal-anti-inflammatory-drugs-nsaids-drug-safety-communication-avoid-use-nsaids-pregnancy-20 - FDA Drug Safety Communication: NSAIDs in pregnancy
https://www.fda.gov/drugs/drug-safety-and-availability/fda-recommends-avoiding-use-nsaids-pregnancy-20-weeks-or-later-because-they-can-result-low-amniotic - DailyMed/Advil labeling
https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020402Orig1s027lbl.pdf