Is Cefdinir Safe in Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

Limited human pregnancy data. Use only if needed and after provider review.

Drug Information

Brand Name
Omnicef
Generic Name
cefdinir
Drug Class
third-generation cephalosporin antibiotic
FDA Category
B
Rx Status
prescription

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy
Crosses the placenta; use only when benefits outweigh risks.
Mother
May cause diarrhea, nausea, or allergic reactions.
Baby
Animal data did not show birth defects; human data are limited.

Trimester Notes

1st Trimester
No specific first-trimester warning in official labeling found. Human data are limited.
2nd Trimester
No specific second-trimester warning in official labeling found. Human data are limited.
3rd Trimester
No specific third-trimester warning in official labeling found. Use only if needed.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • Prescription drug: do not stop or continue without provider review
  • Limited human pregnancy data
  • Allergy to cephalosporins or penicillins
  • Kidney disease may require dose adjustment

Alternatives

  • Amoxicillin if appropriate and prescribed
  • Cephalexin if appropriate and prescribed
  • Nitrofurantoin for some UTIs if prescribed by your provider

References

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