Is Gravol Safe in Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

Pregnancy data are limited but reassuring; use only if needed and with provider guidance.

Drug Information

Brand Name
Gravol
Generic Name
dimenhydrinate
Drug Class
first-generation antihistamine; antiemetic
FDA Category
B
Rx Status
OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy
May help nausea and vomiting; official guidance does not list a routine pregnancy-specific dose.
Mother
Can cause sleepiness, dry mouth, dizziness, and confusion.
Baby
May cause drowsiness in the newborn if used near delivery; limited data do not show a clear increase in birth defects.

Trimester Notes

1st Trimester
Limited data are reassuring, but use only if needed and with provider guidance.
2nd Trimester
Limited data are reassuring, but use only if needed and with provider guidance.
3rd Trimester
Use extra caution near delivery. Drowsiness in the newborn is possible.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • OTC pregnancy dosing limits may apply
  • Use caution near delivery
  • Do not combine with other sedating medicines unless your prescriber says it is okay

Alternatives

  • Vitamin B6 (pyridoxine) if recommended by your provider
  • Doxylamine-pyridoxine if prescribed or advised by your obstetric clinician
  • Non-drug measures such as small frequent meals and fluid sips

References

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