Safe Medications During Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

Hay fever medicines vary. Some antihistamines may be used in pregnancy, but choice depends on the exact drug.

Drug Information

Brand Name
null
Generic Name
null
Drug Class
antihistamine / hay fever medication
FDA Category
unknown
Rx Status
unknown

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy
Some decongestants, like pseudoephedrine, should not be used in the first 3 months.
Mother
May cause drowsiness or dry mouth. Decongestants can raise blood pressure.
Baby
Some antihistamines have reassuring data; others have limited pregnancy data.

Trimester Notes

1st Trimester
Avoid pseudoephedrine in the first 3 months of pregnancy. Some antihistamines are preferred over others.
2nd Trimester
Choice of medicine still depends on the exact ingredient. Check with your prescriber before use.
3rd Trimester
Some medicines may cause more drowsiness in the mother. Ask your prescriber which product fits your symptoms.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • If OTC, pregnancy dosing limits may apply
  • Avoid pseudoephedrine in the first trimester unless your prescriber says otherwise

Alternatives

  • saline nasal spray
  • non-drug measures like avoiding pollen and using a mask outdoors
  • intranasal corticosteroid options only if your clinician recommends them

References

  • ACOG
    https://www.acog.org/womens-health/experts-and-stories/ask-acog/what-medicine-can-i-take-for-allergies-while-im-pregnant
  • NHS SPS
    https://www.sps.nhs.uk/articles/hayfever-or-allergic-rhinitis-treatment-during-pregnancy/
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