Is Loratadine Safe in Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

Limited pregnancy data; official sources say it may be used when needed, with provider review.

Drug Information

Brand Name
Claritin
Generic Name
loratadine
Drug Class
Second-generation antihistamine
FDA Category
B
Rx Status
OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy
Not expected to increase preterm birth or low birth weight based on available official data.
Mother
May help allergy symptoms; can still cause side effects such as drowsiness in some people.
Baby
Not expected to raise birth defect risk above background based on available official data.

Trimester Notes

1st Trimester
Official sources do not show an increased birth defect risk, but data are limited; ask your provider.
2nd Trimester
May be used if needed under provider guidance.
3rd Trimester
May be used if needed, but ask your provider before use, especially near delivery.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • OTC pregnancy dosing limits may apply

Alternatives

  • Saline nasal spray
  • Corticosteroid nasal spray if recommended by your provider
  • Chlorpheniramine only if your provider recommends it

References

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