Is Melatonin Safe in Pregnancy

Reason

Limited pregnancy data. Official sources advise discussing use with your provider before taking melatonin in pregnancy.

Drug Information

Brand Name

Melatonin

Generic Name

melatonin

Drug Class

Hormone; sleep aid

FDA Category

N/A (PLLR narrative label)

Rx Status

OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy

Limited official data on pregnancy safety. Use only if your provider thinks benefits outweigh unknown risks.

Mother

May cause drowsiness, dizziness, and next-day sleepiness.

Baby

May cross the placenta. Human pregnancy data are limited, so effects on the baby are not well defined.

Trimester Notes

1st Trimester

Human data are limited in early pregnancy. Discuss before use.

2nd Trimester

Human data remain limited. Discuss before use.

3rd Trimester

Late-pregnancy fetal effects are not well established. Use only with provider guidance.

Conditions & Warnings

• Consult OB/GYN or prescriber
• OTC product; pregnancy dosing limits may apply
• Do not self-treat chronic insomnia in pregnancy
• Tell your provider about all sleep aids and supplements

Alternatives

• Sleep hygiene measures
• CBT-I or behavioral sleep therapy
• Doxylamine only if your OB/GYN or prescriber recommends it

References

• NHS
  https://www.nhs.uk/medicines/melatonin/
• FDA
  https://www.accessdata.fda.gov/