Is Niacinamide Safe During Pregnancy

Reason

Limited official pregnancy data. Use only if your prescriber recommends it.

Drug Information

Brand Name

null

Generic Name

niacinamide

Drug Class

Vitamin B3 (niacinamide); nutritional supplement

FDA Category

N/A (PLLR narrative label)

Rx Status

OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy

Limited pregnancy-specific labeling. Use only when the benefit outweighs the unknown risk.

Mother

May cause side effects if taken in high amounts, including stomach upset or liver problems.

Baby

No clear FDA pregnancy safety data found for niacinamide as a medicine. High doses should be avoided unless prescribed.

Trimester Notes

1st Trimester

No trimester-specific official guidance found. Because data are limited, avoid nonessential high-dose use.

2nd Trimester

No trimester-specific official guidance found. Use only if your prescriber says the benefit is needed.

3rd Trimester

No trimester-specific official guidance found. Use only if recommended by your prescriber.

Conditions & Warnings

• Consult OB/GYN or prescriber
• OTC pregnancy dosing limits may apply
• Limited official data. Consult your prescriber.

Alternatives

• Food sources of vitamin B3 such as a balanced prenatal diet
• Prenatal vitamin with the amount recommended by your provider

References

• FDA Cosmetics & Pregnancy
  https://www.fda.gov/cosmetics/resources-consumers-cosmetics/cosmetics-pregnancy
• FDA Dietary Supplement Labeling Guide Appendix C
  https://www.fda.gov/food/dietary-supplements-guidance-documents-regulatory-information/dietary-supplement-labeling-guide-appendix-c-daily-values-infants-children-less-4-years-age-and