Is it Safe to Take Paracetamol During Pregnancy

Reason

Can be used in pregnancy when needed, at the lowest effective dose and shortest time.

Drug Information

Brand Name

Paracetamol

Generic Name

acetaminophen

Drug Class

analgesic/antipyretic

FDA Category

N/A (PLLR narrative label)

Rx Status

OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy

Use the lowest effective dose for the shortest possible time. Pregnancy dosing limits may apply.

Mother

May relieve pain and fever. Overuse can harm the liver.

Baby

Official guidance says no clear evidence of harm at recommended doses, but use only when needed.

Trimester Notes

1st Trimester

Can be used when needed. Use the lowest effective dose.

2nd Trimester

Can be used when needed. Use the shortest possible time.

3rd Trimester

Use only when needed and at the lowest effective dose. Seek advice if you need it often.

Conditions & Warnings

• Consult OB/GYN or prescriber
• Pregnancy dosing limits may apply
• Do not combine with other acetaminophen/paracetamol products

Alternatives

• Non-medicine measures such as rest, fluids, cold/warm compresses
• Ask your OB/GYN or prescriber about other options for your symptom

References

• EMA
  https://www.ema.europa.eu/en/news/use-paracetamol-during-pregnancy-unchanged-eu
• ACOG
  https://www.acog.org/news/news-articles/2021/09/response-to-consensus-statement-on-paracetamol-use-during-pregnancy
• CDC
  https://www.cdc.gov/medicine-and-pregnancy/about/index.html