Is Pepto Bismol Safe in Pregnancy

Status

avoid Last reviewed: 2026-05-16 · Confidence: high

Reason

Official NHS and CDC guidance says do not use in pregnancy or breastfeeding; salicylate exposure may harm the baby.

Drug Information

Brand Name
Pepto-Bismol
Generic Name
bismuth subsalicylate
Drug Class
antidiarrheal; antacid; antiemetic (salicylate-containing bismuth compound)
FDA Category
C
Rx Status
OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit. Pregnancy use is not recommended.

Effects

Pregnancy
Not recommended in pregnancy. NHS says avoid, especially with regular use after 30 weeks.
Mother
May cause black tongue or black stools; overdose can cause ringing in ears, dizziness, confusion, or hearing changes.
Baby
Possible salicylate exposure may affect fetal bleeding risk; avoid especially after 30 weeks.

Trimester Notes

1st Trimester
Avoid unless a prescriber specifically recommends it.
2nd Trimester
Avoid unless a prescriber specifically recommends it.
3rd Trimester
Avoid, especially after 30 weeks. NHS warns regular use may affect the baby.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • Pregnant
  • Breastfeeding
  • History of aspirin allergy
  • Bleeding disorder
  • Gout
  • Diabetes
  • Phenylketonuria (chewable tablets may contain aspartame)

Alternatives

  • Oral rehydration solution for diarrhea
  • Diet changes for indigestion
  • Ask OB/GYN or pharmacist for pregnancy-appropriate treatment

References

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