Is Simethicone Safe in Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

OTC gas medicine with limited pregnancy data; official sources say it is not absorbed and is generally considered acceptable, but use as directed.

Drug Information

Brand Name
Gas-X, Mylicon, Phazyme
Generic Name
simethicone
Drug Class
antiflatulent
FDA Category
N/A (PLLR narrative label)
Rx Status
OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit. Follow the package label if your clinician approves use.

Effects

Pregnancy
No specific pregnancy warning in official labeling; use only as directed and check with your provider if symptoms persist.
Mother
May help relieve gas and bloating. Side effects are uncommon.
Baby
No systemic absorption expected; fetal exposure is not expected to be meaningful.

Trimester Notes

1st Trimester
No trimester-specific warning found in official sources. Limited official pregnancy data.
2nd Trimester
No trimester-specific warning found in official sources. Use only as directed.
3rd Trimester
No trimester-specific warning found in official sources. Use only as directed.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • OTC pregnancy dosing limits may apply

Alternatives

  • Lifestyle measures for gas relief as advised by your clinician
  • Other OTC options only after pharmacist or prescriber review

References

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