Is Zyrtec Safe During Pregnancy

Status

caution Last reviewed: 2026-05-16 · Confidence: moderate

Reason

Limited official pregnancy data. NHS and ACOG say cetirizine may be used in pregnancy, but provider review is advised.

Drug Information

Brand Name
Zyrtec
Generic Name
cetirizine
Drug Class
Second-generation antihistamine
FDA Category
N/A (PLLR narrative label)
Rx Status
OTC

Safe Amount

Dosage must be determined by your provider based on individual risk/benefit.

Effects

Pregnancy
No official pregnancy dose is set; use should be reviewed with a prescriber.
Mother
May help allergy symptoms; can cause drowsiness in some people.
Baby
No clear suggestion of harm from official guidance, but data are limited.

Trimester Notes

1st Trimester
No specific first-trimester warning found in official sources cited here; discuss use with your prescriber.
2nd Trimester
No specific second-trimester warning found in official sources cited here; discuss use with your prescriber.
3rd Trimester
NHS and ACOG do not list a special third-trimester warning for cetirizine.

Conditions & Warnings

  • Consult OB/GYN or prescriber
  • OTC pregnancy dosing limits may apply

Alternatives

  • Nasal saline spray
  • Other allergy medicines only if your OB/GYN or prescriber recommends them
  • Non-drug allergy control such as avoiding triggers

References

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